Publications - Last 5 Years




Carroll MW, Gill H, Simkin J, Smyth M, Hamilton, Z, Bressler B, Jacobson K. Pediatric Inflammatory Bowel Disease amongst South Asians living in British Columbia, Canada: A distinct clinical phenotype. Inflamm Bowel Disease. Accepted for publication Sept 12, 2015.


Ngoh EN, Weisser SB, Lo Y, Kozicky LK, Jen R, Brugger HK, Menzies SC, McLarren KW, Nackiewicz D, van Rooijen N, Jacobson K, Ehses JA, Turvey SE, Sly LM. Activity of SHIP, which prevents expression of interleukin-1β, is reduced in patients with Crohn's disease. Gastroenterology. 2015 Oct 16.


Ryz NR, Lochner A, Bhullar K, Ma C, Huang T, Bhinder G, Bosman E, Wu X, Innis SM, Jacobson K, Vallance BA. Dietary vitamin D3 deficiency alters intestinal mucosal defense and increases susceptibility to Citrobacter rodentium induced colitis. Am J Physiol Gastrointest Liver Physiol. 2015 Sep 3.


Ngoh EN, Brugger HK, Monajemi M, Menzies SC, Hirschfeld AF, Del Bel KL, Jacobson K, Lavoie PM, Turvey SE, Sly LM. The Crohn's disease-associated polymorphism in ATG16L1 (rs2241880) reduces SHIP gene expression and activity in human subjects. Genes Immun. 2015 Oct;16(7):452-61.


Wu X, Conlin VS, Morampudi V, Ryz NR, Nasser Y, Bhinder G, Bergstrom KS, Yu HB, Waterhouse CC, Buchan AM, Popescu OE, Gibson WT, Waschek JA, Vallance BA, Jacobson K. Vasoactive intestinal polypeptide promotes intestinal barrier homeostasis and protection against colitis in mice. PLoS One. 2015 May 1;10(5):e0125225. 


Morampudi V, Conlin VS, Dalwadi U, Wu X, Marshall KC, Nguyen C, Vallance BA, Jacobson K. Vasoactive intestinal peptide prevents PKCε-induced intestinal epithelial barrier disruption during EPEC infection. Am J Physiol Gastrointest Liver Physiol. 2015 Mar 1;308(5):G389-402.


Hasosah M, Satti M, Shehzad A, Alsahafi A, Sukkar G, Alzaben A, Sunaid A, Ahmed A, Al Thubiti S, Mufti A, Jacobson K.  Prevalence and risk factors of Helicobacter pylori infection in Saudi Children: Three-year prospective controlled study. Helicobacter. 2015 Feb;20(1):56-63.


Gibson DL, Gill S, Brown K, Tasmin N, Ghosh S, Innis S. Jacobson K. Maternal exposure to fish oil primes offspring to harbour intestinal pathobionts associated with altered immune cell balance. Gut Microbes. 2015 Jan 2;6(1):24-32.


Antunes C, McDonald J, Schroeter K, Carlucci C, Ferreira R, Wang M, Yurist-Doutsch S, Hira G, Jacobson K, Davies J, Allen-Vercoe E, Finlay BB. Anti-virulence activity of the human gut metabolome. MBio. 2014 Jul 29;5(4):e01183-14. 


Bhinder G, Stahl M, Sham HP, Crowley SM, Morampudi V, Dalwadi U, Ma C, Jacobson K, Vallance BA. Intestinal epithelium-specific MyD88 signaling impacts host susceptibility to infectious colitis by promoting protective goblet cell and antimicrobial responses. Infect Immun. 2014 Sep;82(9):3753-63.


Morampudi V, Bhinder G, Wu X, Dai C, Sham HP, Vallance BA, Jacobson K. DNBS/TNBS colitis models: providing insights into inflammatory bowel disease and effects of dietary fat. J Vis Exp. 2014 Feb 27;(84):e51297. 


Wingate KE, Jacobson K, Issenman RM, Carroll MW, Barker C, Israel D, Brill H, Weiler H, Barr SI, Li W, Lyon MR, Green, TJ.  25-hydroxyvitamin D concentrations in children with Crohn's disease supplemented with either 2000 or 400 IU daily for 6 months: a randomized controlled study. J Pediatr. 2014 Apr;164(4):860-5.


Foster A, Jacobson K. Changing incidence of inflammatory bowel disease: environmental influences and lessons learnt from the South Asian population. Front Pediatr. 2013 Nov 6;1:34. eCollection 2013.


Jamieson DH, Shipman P, Jacobson K. Magnetic resonance imaging of the perineum in pediatric patients with inflammatory bowel disease. Can J Gastroenterol. 2013 Aug;27(8): 476-80.


Eslamian G, Jacobson K, Hekmatdoost A. Clinical nutrition knowledge of Gastroenterology Fellows: Is there anything omitted? Acta Med Iran. 2013 Sep;51(9):633-7.


Hasosah MY, Sukkar GA, Alsahafi AF, Kutbi SY, Alzabn AA, Jacobson K. Pediatric Inflammatory Bowel Disease in the Western regions of Saudi Arabia. A retrospective analysis. Saudi Med J. 2013 Jun;34(6):651-3. 


Bhinder G, Sham HP, Chan JM, Morampudi V, Jacobson K, Vallance BA. The Citrobacter rodentium mouse model: studying pathogen and host contributions to infectious colitis. J Vis Exp. 2013 Feb 19;(72):e50222.


Hekmatdoost A. Xiujuan Wu, Innis SM, Jacobson K. Dietary Oils modify the host immune response and colonic tissue damage following Citrobacter rodentium-infection in Mice. Am J Physiol Gastrointest Liver Physiol. 2013 May 15;304(10):G917-28.


Ryz NR, Patterson SJ, Zhang Y, Ma C, Huang T, Bhinder G, Wu X, Chan J, Glesby A, Sham HP, Dutz JP, Levings MK, Jacobson K, Vallance BA. Active vitamin D (1,25-dihydroxyvitamin D3) increases host susceptibility to Citrobacter rodentium by suppressing mucosal Th17 responses. Am J Physiol Gastrointest Liver Physiol. 2012 Dec 15;303(12):G1299-311. 


Hasosah MY, Kutbi SY, Al-Amri AW, Alsahafi AF, Sukkar GA, Alghamdi KJ, Jacobson K. Perinatal cytomegalovirus hepatitis in Saudi infants: A case series. Saudi J Gastroenterol. 2012 May-June;18(3):208-13.


Hasosah MY, Ghandourah HS, Alsahafi AF, Sukkar GA, Jacobson K. Seroconversion of hepatitis B envelope antigen (HBeAg) by entecavir in a child with chronic hepatitis B. Saudi J Gastroenterol. 2012 May-June;18(3):217-20.


Al Riyami AZ, Jacobson K, Ford J, Dalal BI. Transient appearance of GPI-deficient population in a patient with azathioprine-associated bone marrow aplasia. Ann Hematol. Oct;91(10):1659-61.


Carroll MW, Jacobson K. Gastroesophageal reflux disease in children and adolescents: When and how to treat. Paediatr Drugs. 2012 Apr 1;14(2):79-89.


Jones NL, Chiba N, Fallone C, Thompson A, Hunt R, Jacobson K, Goodman K; Canadian Helicobacter study group participants. Helicobacter pylori in First Nation and Recent Immigrant Populations in Canada. Canadian J Gastroenterol, 2012 Feb;26(2):97-103.


Hyams J, Damaraju L, Blank M, Johanns J, Guzzo C, Winters HS, Kugathason S, Cohen S, Markowitz J, Escher JC, Veereman-Wauters G, Crandall W, Baldassano R, Griffiths A, T72 study group (Jacobson K).  Induction and maintenance therapy with infliximab for children with moderate to severe ulcerative colitis. Clin Gastroenterol Hepatol. 2012 Apr 10;(4)391-9.


Hasosah M, Baothman A, Satti M, Al-Ghamdi KJ, Kutbi S, Jacobson K. Mucosa-Associated Lymphoid Tissue Lymphoma of the Lacrimal Gland: Sustained Remission after Eradication of Helicobacter Pylori Infection. Case Reports in Gastrointestinal Med. 2011; 2011:94572.


McLarren KW, Cole AE, Weisser SB, Voglmaier NS, Conlin VS, Jacobson K, Popescu O, Boucher JL, Sly LM. SHIP-deficient mice develop spontaneous intestinal inflammation and arginase-dependent fibrosis. Am J Pathol. 2011 Jul;179(1):180-8.


Innis SM, Dai C, Wu X, Buchan AMJ, Jacobson K. Perinatal Lipid Nutrition Alters Early Intestinal Development and Programs the Response to Experimental Colitis in Young Adult Rats. Am J Physiol Gastrointest Liver Physiol. 2010 Dec;299(6):G1376-85. 


Xiao H, Yin W, Khan MA, Gulen MF, Zhou H, Sham HP, Jacobson K, Vallance BA, Li X. Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice. Gastroenterology. 2010 Aug;139(2):574-85.